About
I am a Research Scientist at Seattle Children's Research Institute in the Center for Integrative Brain Research. My research combines computational neuroscience and experimental circuit dissection to understand how opioids simultaneously affect breathing and pain — with the long-term goal of identifying strategies to preserve analgesia while preventing life-threatening respiratory depression.
I studied physics at Portland State before joining Mary Heinricher's lab at OHSU, where I first discovered the link between pain-facilitating RVM neurons and opioid-induced respiratory depression. I completed my Ph.D. through the NIH–University of New Hampshire joint program, working with Jeffrey Smith at NINDS to build data-driven computational models of the preBötzinger complex — work featured in an eLife Insight article. My postdoc with Jonathan Rubin at the University of Pittsburgh deepened my mathematical neuroscience toolkit, producing the first biophysical implementation of burstlet theory and models of basal ganglia dynamics.
At Seattle Children's, I'm bringing these threads together through my NIH K01 award (NIDA, 4th percentile), using Neuropixels recordings, fiber photometry, and intersectional genetics alongside biophysical modeling to dissect cell-type-specific mechanisms in the brainstem. I also build open-source software tools that bring modern ML approaches to physiology labs.
Training
Seattle Children's Research Institute · Center for Integrative Brain Research
Seattle Children's Research Institute · with Nathan Baertsch
University of Pittsburgh, Dept. of Mathematics · with Jonathan Rubin
NIH & University of New Hampshire — Joint Program · with Jeffrey C. Smith (NINDS)
Oregon Health & Science University · with Mary M. Heinricher
Portland State University
Mentoring & Teaching
I have mentored 6 trainees across career stages — from high school through undergraduate — in computational and experimental neuroscience projects at Seattle Children's, the University of Pittsburgh, and through the NIH Summer Internship Program. Two mentees presented their work at national conferences.
I was Instructor of Record for Calculus at the University of Pittsburgh (4 semesters) and a Graduate Teaching Assistant for physics labs at the University of New Hampshire (4 semesters). I hold a Cognate in College Teaching from UNH.
Service
Review Editor for Frontiers in Computational Neuroscience. Ad hoc reviewer for eLife, PLOS Computational Biology, Journal of Neuroscience, Journal of Physiology, and others. Co-organized the 2018 Complex Systems in Neuroscience conference at the University of Pittsburgh.
Curriculum Vitae
Full CV with complete publication list, invited talks, and professional activities.
Download CV (PDF)